James Cook III
NFL Injury Report

James Cook III Injury Status

Buffalo Bills • RB
Latest Injury Status
active
A

Cook was repeatedly stonewalled through three quarters by a Vikings run defense that had been fairly beatable, but the star running back continued to get opportunities to test Minnesota's defensive front. That approach finally began paying off on an early fourth-quarter marathon scoring drive, one where Cook recorded runs of nine, six and 11 yards before capping off the march with a five-yard scoring rush to extend Buffalo's 13-6 lead. Cook ultimately fell just a carry short of tying his career high, and he eclipsed the century mark on the ground for the fourth time this season. The fifth-year pro's trip to the end zone extended his touchdown streak to seven games as well, and Cook will head into a favorable Week 10 road matchup against the Jets just 186 rushing yards short of his fourth straight 1,000-yard campaign.

Injury Details

Body Part
—
Location
—
Side
—
Expected Return
Not announced

Betting Research

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James Cook III Injury History

November 13, 2026
active
Cook rushed 31 times for 107 yards and a touchdown and failed to bring in his only target in the Bills' 23-6 win over the Vikings on Monday night.
November 10, 2026
active
Cook rushed 21 times for 80 yards and a touchdown while catching two of three targets for 21 yards in Sunday's 36-10 win over the Ravens.
November 2, 2026
active
Cook (undisclosed) headed to the blue medical tent during Sunday's game against the Ravens after absorbing a hard hit, Matt Parrino reports.
November 1, 2026
active
After being evaluated for a head injury, Cook was cleared to return to Sunday's game against the Ravens.
November 1, 2026
questionable • Undisclosed
questionable
October 29, 2026
active
Cook rushed 22 times for 95 yards and a touchdown and brought in all three targets for 58 yards in the Bills' 33-30 win over the Raiders on Sunday.
October 19, 2026
active
Cook rushed 10 times for 121 yards and a touchdown and brought in his only target for seven yards in the Bills' 37-34 overtime win over the Rams on Monday night. He also committed two fumbles, losing one.
October 13, 2026
active
Cook rushed 12 times for 75 yards and a touchdown and brought in both targets for eight yards in the Bills' 29-26 loss to the Patriots on Sunday.
October 4, 2026
active
Cook rushed 24 times for 154 yards and a touchdown and failed to bring in his only target in the Bills' 24-16 win over the Chargers on Sunday. He also lost a fumble.
September 27, 2026
active
Cook rushed 21 times for 135 yards and a touchdown and brought in one of three targets for four yards in the Bills' 41-31 win over the Lions on Thursday.
September 18, 2026
active
Cook rushed 13 times for 57 yards and caught three of four targets for 12 yards in Sunday's 36-31 win over the Texans.
September 13, 2026
active
Cook didn't play during Buffalo's exhibition win over Pittsburgh on Thursday.
August 29, 2026
active
Cook carried the ball five times for 21 yards in Saturday's 29-14 preseason win over the Panthers.

Latest James Cook III Injury Updates

This page tracks available injury information for James Cook III, including reported status, injury details, expected return information and updates that may be relevant when evaluating NFL betting markets.

Injury designations can change close to game time. Check the latest market prices and confirmed player availability before placing a wager.